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Practical aspects of the use of target controlled infusion with remifentanil in neurosurgical patients: predicted cerebral concentrations at intubation, incision and extubation
| dc.contributor.author | Ferreira, D. | |
| dc.contributor.author | Nunes, C. | |
| dc.contributor.author | Antunes, L. | |
| dc.contributor.author | Lobo, F. | |
| dc.contributor.author | Amorim, P. | |
| dc.date.accessioned | 2011-08-23T12:03:15Z | |
| dc.date.available | 2011-08-23T12:03:15Z | |
| dc.date.issued | 2006 | |
| dc.description.abstract | Abstract Remifentanil has important side effects and it is not easy to know what remifentanil concentrations should be used during different endpoints of anaesthesia. We analyzed the remifentanil predicted effect-site concentrations (RemiCe) at different events during neurosurgical procedures and assessed if the concentrations used were clinically adequate. BIS and haemodynamic parameters were collected every 5 seconds. Predicted cerebral concentration of propofol (PropCe) and RemiCe were analyzed immediately prior to respective stimulus, and 30, 60 and 90 seconds after. RemiCe were 2.2 +/- 0.3, 6 +/- 2.6 and 2.2 +/- 0.9 ng ml(-1) at intubation, incision and extubation, respectively. PropCe observed in the same periods were 5 +/- 1, 2.6 +/- 0.9 and 1 +/- 0.3 microg ml(-1), also respectively. The remifentanil concentrations used in our patients were lower than reported concentrations, while being clinically adequate to minimize the haemodynamic response to stimulation. | por |
| dc.identifier.citation | Acta Anaesthesiol Belg. 2006;57(3):265-70. | por |
| dc.identifier.issn | 0001-5164 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/817 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Société belge d'anesthésie et de réanimation | por |
| dc.relation.publisherversion | http://www.sarb.be/fr/journal/artikels_acta_2006/artikels_acta_57_3/06-Ferreira.pdf | por |
| dc.subject | Remifentanil | por |
| dc.subject | intubation | por |
| dc.subject | incision | por |
| dc.subject | extubation | por |
| dc.title | Practical aspects of the use of target controlled infusion with remifentanil in neurosurgical patients: predicted cerebral concentrations at intubation, incision and extubation | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Belgica | por |
| oaire.citation.endPage | 270 | por |
| oaire.citation.issue | 57(3) | por |
| oaire.citation.startPage | 265 | por |
| oaire.citation.title | Acta anaesthesiologica Belgica | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
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