Publication
Azathioprine-Induced Acute Submandibular Sialadenitis in a Crohn's Disease Patient
| dc.contributor.author | Alves da Silva, Joana Inês | |
| dc.contributor.author | Caetano, Cidalina | |
| dc.contributor.author | Pedroto, Isabel | |
| dc.date.accessioned | 2021-05-20T14:29:54Z | |
| dc.date.available | 2021-05-20T14:29:54Z | |
| dc.date.issued | 2020-08 | |
| dc.description.abstract | Introduction: Azathioprine (AZA) is a widely used immunosuppressive drug in inflammatory bowel disease (IBD). The occurrence of adverse effects (AEs) is a major downside in the use of this drug, leading to treatment withdrawal in a variable proportion of patients. Case presentation: We report the case of a Crohn's disease patient who developed sialadenitis as an AE to AZA. Discussion and conclusion: To our knowledge this AE has been reported only once in the literature. Sialadenitis is a common disorder and refers to inflammation of a salivary gland. It has many causes, such as bacterial and viral infections, ductal obstruction, and drugs. There are several AEs related to this drug, categorized as dose-dependent and dose-independent. Their knowledge is essential for therapeutic management in IBD, which is already challenging, requiring an individualized approach. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Alves da Silva JI, Caetano C, Pedroto I. Azathioprine-Induced Acute Submandibular Sialadenitis in a Crohn's Disease Patient. GE Port J Gastroenterol. 2020 Aug;27(5):361-363. doi: 10.1159/000505037. Epub 2020 Jan 7. PMID: 32999909; PMCID: PMC7506223. | pt_PT |
| dc.identifier.doi | 10.1159/000505037 | pt_PT |
| dc.identifier.issn | 2341-4545 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/2456 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Karger Publishers | pt_PT |
| dc.relation.publisherversion | https://www.karger.com/Article/FullText/505037 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | pt_PT |
| dc.subject | Azathioprine | pt_PT |
| dc.subject | Adverse effect | pt_PT |
| dc.subject | Sialadenitis | pt_PT |
| dc.subject | Crohn’s disease | pt_PT |
| dc.title | Azathioprine-Induced Acute Submandibular Sialadenitis in a Crohn's Disease Patient | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Switzerland | pt_PT |
| oaire.citation.endPage | 363 | pt_PT |
| oaire.citation.issue | 5 | pt_PT |
| oaire.citation.startPage | 361 | pt_PT |
| oaire.citation.title | GE Portuguese journal of gastroenterology | pt_PT |
| oaire.citation.volume | 27 | pt_PT |
| person.familyName | Pedroto | |
| person.givenName | Isabel | |
| person.identifier.orcid | 0000-0001-6573-699X | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | e523f164-bf0d-4248-8069-53df9d926349 | |
| relation.isAuthorOfPublication.latestForDiscovery | e523f164-bf0d-4248-8069-53df9d926349 |
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