Publication
SARS-CoV-2 and hearing: An audiometric analysis of COVID-19 hospitalized patients
| dc.contributor.author | Sousa, Francisco Alves De | |
| dc.contributor.author | Pinto Costa, Rodrigo | |
| dc.contributor.author | Xará, Sandra | |
| dc.contributor.author | Nóbrega Pinto, Ana | |
| dc.contributor.author | Almeida e Sousa, Cecília | |
| dc.date.accessioned | 2023-10-17T11:17:52Z | |
| dc.date.available | 2023-10-17T11:17:52Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Purpose: COVID-19 associated hearing loss is still an ongoing matter of debate. No original studies exist on audiological effects of SARS-CoV-2 infection in hospitalized patients. The main objective was to determine whether SARS-CoV-2 may affect auditory function in clinically ill COVID-19 patients. Materials and methods: COVID-19 patients with moderate-severe disease and without prior history of hearing abnormalities were enrolled from a tertiary referral center, and matched with controls. Participants performed an audiometric evaluation, and thresholds were compared. Results: 120 ears from 60 patients were enrolled. Patients with COVID-19 showed worse mean auditory thresholds starting from 1000 Hz through higher frequencies, when compared to controls (1000 Hz: 18.52 ± 5.49 dB HL in controls vs 25.36 ± 6.79 dB HL in COVID-19, p < 0.001; 2000Hz: 17.50 ± 5.57 dB HL in controls vs 21.96 ± 7.05 dB HL in COVID-19, p = 0.010; 3000Hz: 17.97 ± 8.07 dB HL in controls vs 25 ± 9.38 dB HL in COVID-19, p = 0.003; 4000 Hz: 20.16 ± 10.12 dB HL in controls vs 29.55 ± 11.26 dB HL in COVID-19, p = 0.001; 8000 Hz: 31.09 ± 12.75 dB HL in controls vs 40.71 ± 19.40 dB HL in COVID-19, p = 0.030; Pure Tone Average: 20.42 ± 4.29 dB HL in controls vs 24.85 ± 5.62 dB HL in COVID-19, p = 0.001). Statistical significance persisted after adjusting for confounders such as age, gender and various comorbidities (p < 0.05). Conclusions: SARS-CoV-2 may affect hearing in COVID-19 patients with moderate-severe disease. Results are in line with the previous suggested effects of COVID-19 on auditory system. This study is expected to encourage further research on this topic. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Alves de Sousa F, Pinto Costa R, Xará S, Nóbrega Pinto A, Almeida E Sousa C. SARS-CoV-2 and hearing: An audiometric analysis of COVID-19 hospitalized patients. J Otol. 2021;16(3):158-164. doi:10.1016/j.joto.2021.01.005 | pt_PT |
| dc.identifier.doi | 10.1016/j.joto.2021.01.005 | pt_PT |
| dc.identifier.issn | 1672-2930 | |
| dc.identifier.issn | 2524-1753 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/2811 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Elsevier | pt_PT |
| dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1672293021000052?via%3Dihub | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | Audiometry | pt_PT |
| dc.subject | COVID-19 | pt_PT |
| dc.subject | Coronavirus | pt_PT |
| dc.subject | Hearing; SARS-CoV-2 | pt_PT |
| dc.title | SARS-CoV-2 and hearing: An audiometric analysis of COVID-19 hospitalized patients | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | China | pt_PT |
| oaire.citation.endPage | 164 | pt_PT |
| oaire.citation.issue | 3 | pt_PT |
| oaire.citation.startPage | 158 | pt_PT |
| oaire.citation.title | Journal of Otology | pt_PT |
| oaire.citation.volume | 16 | pt_PT |
| person.familyName | Sousa | |
| person.givenName | Francisco Alves de | |
| person.identifier.orcid | 0000-0003-4113-3259 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 6d0cf218-638a-4b17-8bdf-30203de52429 | |
| relation.isAuthorOfPublication.latestForDiscovery | 6d0cf218-638a-4b17-8bdf-30203de52429 |