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Effect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltration

dc.contributor.authorMoura, A.
dc.contributor.authorMadureira, J.
dc.contributor.authorAlija, P.
dc.contributor.authorFernandes, J.
dc.contributor.authorOliveira, J.
dc.contributor.authorLopez, M.
dc.contributor.authorFilgueiras, M.
dc.contributor.authorAmado, L.
dc.contributor.authorSameiro-Faria, M.
dc.contributor.authorMiranda, V.
dc.contributor.authorSantos-Silva, A.
dc.contributor.authorCosta, E.
dc.date.accessioned2015-07-14T10:08:11Z
dc.date.available2015-07-14T10:08:11Z
dc.date.issued2014
dc.description.abstractThis work aimed to evaluate how aging could influence patients’ perception of health quality of life (HRQOL), as well as, the effect of aging on dialysis adequacy and in hematological, iron status, inflammatory and nutritional markers. In this transversal study were enrolled 305 ESRD patients under Online-hemodiafiltration (OL-HDF) (59.67% males; 64.9 ± 14.3 years old). Data about comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patient’s records. Moreover, HRQOL score, by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF), was assessed. Analyzing the results according to quartiles of age, significant differences were found for some parameters evaluated by the KDQOL-SF instrument, namely for work status, physical functioning and role-physical, which decreased with increasing age. We also found a higher proportion of diabetic patients, a decrease in creatinine, iron, albumin serum levels, transferrin saturation and nPCR, with increasing age. Moreover, significant negative correlations were found between age and mean cell hemoglobin concentration, iron, transferrin saturation, albumin, nPCR, work status, physical functioning and role-physical. In conclusion, our results showed that aging is associated with a decreased work status, physical functioning and role-physical, with a decreased dialysis adequacy, iron availability and nutritional status, and with an increased proportion of diabetic patients and of patients using central venous catheter, as the vascular access. The knowledge of these changes associated with aging, which have impact in the quality of life of the patients, could be useful in their management.por
dc.identifier.citationAging Dis. 2014. 6(1):17-26.por
dc.identifier.doi10.14336/AD.2014.0514
dc.identifier.issn2152-5250
dc.identifier.urihttp://hdl.handle.net/10400.16/1818
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherJKL Internationalpor
dc.relation.publisherversionhttp://dx.doi.org/10.14336/AD.2014.0514por
dc.subjectHealth - related quality of lifepor
dc.subjecton - line hemodiafiltrationpor
dc.subjectaging,por
dc.subjectgenderpor
dc.subjectdialysis adequacypor
dc.subjectiron availability,por
dc.subjectnutritional statuspor
dc.titleEffect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltrationpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapor
oaire.citation.endPage26por
oaire.citation.startPage17por
oaire.citation.titleAging and diseasepor
oaire.citation.volume6(1)por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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