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Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease

dc.contributor.authorFeldman, H.
dc.contributor.authorMaia, L.
dc.contributor.authorMackenzie, I.
dc.contributor.authorForster, B.
dc.contributor.authorMartzke, J.
dc.contributor.authorWoolfenden, A.
dc.date.accessioned2012-04-23T10:07:21Z
dc.date.available2012-04-23T10:07:21Z
dc.date.issued2008
dc.description.abstractAbstract BACKGROUND AND PURPOSE: Superficial siderosis of the central nervous system results from chronic bleeding in the superficial layers of the cortex and spinal cord. In cerebral amyloid angiopathy (CAA), there is amyloid deposition in meningeal and meningo-cortical arteries and capillaries, predisposing them to rupture. CAA is frequently associated with Alzheimer disease (AD). METHODS: We report a series of 3 AD patients with MRI evidence of superficial siderosis. Two had neuropathological examination confirming superficial siderosis, AD, and CAA. CONCLUSIONS: Superficial siderosis should be recognized within the spectrum of AD with CAA and considered as a possible antemortem diagnostic feature.por
dc.identifier.citationStroke. 2008 Oct;39(10):2894-7por
dc.identifier.issn0039-2499
dc.identifier.urihttp://hdl.handle.net/10400.16/1025
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherAmerican Heart Associationpor
dc.relation.publisherversionhttp://stroke.ahajournals.org/content/39/10/2894.full.pdf+htmlpor
dc.subjectAlzheimer diseasepor
dc.subjectcerebral amyloid angiopathypor
dc.subjectsuperficial siderosispor
dc.titleSuperficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer diseasepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapor
oaire.citation.endPage2897por
oaire.citation.issue39(10)por
oaire.citation.startPage2894por
oaire.citation.titleStrokepor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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