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Uterine artery impedance during the first eight postpartum weeks

dc.contributor.authorGuedes-Martins, L.
dc.contributor.authorGaio, A.
dc.contributor.authorSaraiva, J.
dc.contributor.authorCunha, A.
dc.contributor.authorMacedo, F.
dc.contributor.authorAlmeida, H.
dc.date.accessioned2016-07-19T09:37:12Z
dc.date.available2016-07-19T09:37:12Z
dc.date.issued2015
dc.description.abstractThe aim of this study was to construct reference ranges for the uterine artery (UtA) mean pulsatility (PI) and resistance (RI) indices from 1-8 weeks postpartum. A prospective, cross-sectional, and observational study was performed with 320 healthy women from week 1 through week 8 postpartum. UtAs were examined transvaginally using colour and pulsed Doppler imaging, and the means of the right and left values of the PI and RI, as well as the presence or absence of a bilateral protodiastolic notch, were recorded. The 5(th), 50(th) and 95(th) reference percentile curves for the UtA-PI and UtA-RI were derived using regression models. The adjusted reference intervals uncovered a convergence trend at the week 8 time-point, although impedance was lower at the week 1 time-point in multiparous women compared with primiparous women. The notching prevalence was 22.5% (9/40) at week 1 and 95.0% (38/40) at week 8. The study revealed consistent evidence of a progressive increase of postpartum uterine impedance and provided new average UtA-PI and UtA-RI reference charts for weeks 1 through 8. Multiparity does not change the trend but does impart a lower rate of increase, likely as a consequence of previous vascular structural and functional differences.pt_PT
dc.identifier.citationSci Rep. 2015 Mar 5;5:8786pt_PT
dc.identifier.doi10.1038/srep08786pt_PT
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/10400.16/1955
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherNature Publishing Grouppt_PT
dc.relation.publisherversionhttp://www.nature.com/articles/srep08786pt_PT
dc.subjectAdolescentpt_PT
dc.subjectAdultpt_PT
dc.subjectFemalept_PT
dc.subjectHumanspt_PT
dc.subjectPostpartum Periodpt_PT
dc.subjectPulsatile Flowpt_PT
dc.subjectRisk Factorspt_PT
dc.subjectTime Factorspt_PT
dc.subjectUterine Arterypt_PT
dc.subjectVascular Resistancept_PT
dc.subjectYoung Adultpt_PT
dc.titleUterine artery impedance during the first eight postpartum weekspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceEnglandpt_PT
oaire.citation.startPage8786pt_PT
oaire.citation.titleScientific reportspt_PT
oaire.citation.volume5pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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