Publication
Preterm infants under 27 weeks gestational age: outcomes in a tertiary hospital
| dc.contributor.author | SĆ”, M. | |
| dc.contributor.author | Fonte, M. | |
| dc.contributor.author | Carvalho, C. | |
| dc.contributor.author | Soares, P. | |
| dc.contributor.author | Almeida, A. | |
| dc.contributor.author | JanuƔrio, A. | |
| dc.contributor.author | Gouveia, S. | |
| dc.contributor.author | Saraiva, J. | |
| dc.date.accessioned | 2015-06-01T09:56:02Z | |
| dc.date.available | 2015-06-01T09:56:02Z | |
| dc.date.issued | 2015-03 | |
| dc.description.abstract | Introduction: Over the last decades, survival of extremely preterm infants improved but thereĀ“s still significant morbidity among this group. We pretend to evaluate if specific attitudes/characteristics are associated with higher survival or survival without severe disabilities and elaborate predicting outcome models. Material and Methods: Observational descriptive study, including the 205 liveborn/stillborn infants -gestational age 22w0d-26w6d- born at an Obstetrics Unit or transferred to a Neonatology Unit of a Level III Hospital, from January-2000 to December-2009. We collected variables related to management in the prenatal/neonatal period, neonate performances and psychomotor development (18-24 months). Significant associations between variables/outcomes were identified by chi-square test or t-test; multivariate logistic regression models were used to describe and predict mortality/morbidity. Results: Advanced Gestational Age (GA) (p=0.001), antenatal corticotherapy(p=0.001), cesarean section(p=0.001), inborn delivery(p=0.021) and increased weight(p=0.001) were associated with survival. Absence of Intraventricular Hemorrhage (IVH) grade 3-4(p=0.001) and absence of Periventricular Leukomalacia (PVL) (p=0.005) were associated with survival without severe neurossensorial deficit. According to multivariable models, advanced GA (OR=0.353,CI95% 0.208-0.599), increased weight (OR=0.996,CI95% 0.993-0.999) and antenatal corticotherapy (OR=0.150,CI95% 0.044-0.510) were associated with lower mortality risk. Rupture of membranes less than 12 h duration was associated with higher mortality risk (OR=3.88,CI95% 1.406-10.680). IVH grades 3-4 was associated with higher morbidity risk (OR=16.931,CI95% 2.744-104.452). Mortality and severe morbidity models predicted correctly the outcome in 78.1% and 85.7% of the cases, respectively. Conclusions: Mortality/morbidity models might be valuable tools providing insight in the prediction of the outcome of these neonates and helping parental counseling. | por |
| dc.identifier.citation | Nascer e Crescer 2015;24(1):12-7 | por |
| dc.identifier.issn | 0872-0754 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/1796 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Centro Hospitalar do Porto | por |
| dc.subject | Extremely preterm | por |
| dc.subject | outcomes | por |
| dc.subject | models | por |
| dc.subject | parental counseling | por |
| dc.title | Preterm infants under 27 weeks gestational age: outcomes in a tertiary hospital | por |
| dc.title.alternative | PrƩ-termos abaixo das 27 semanas de idade gestacional: desfechos num hospital terciƔrio. | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Portugal | por |
| oaire.citation.endPage | 17 | por |
| oaire.citation.startPage | 12 | por |
| oaire.citation.title | Revista Nascer e Crescer | por |
| oaire.citation.volume | 24(1) | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |