Publication
Differences in microbiological profile between community-acquired, healthcare-associated and hospital-acquired infections
| dc.contributor.author | Cardoso, T. | |
| dc.contributor.author | Ribeiro, O. | |
| dc.contributor.author | Aragâo, I | |
| dc.contributor.author | Costa-Pereira, A. | |
| dc.contributor.author | Sarmento, A. | |
| dc.date.accessioned | 2014-07-31T15:44:01Z | |
| dc.date.available | 2014-07-31T15:44:01Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | INTRODUCTION: Microbiological profiles were analysed and compared for intra-abdominal, urinary, respiratory and bloodstream infections according to place of acquisition: community-acquired, with a separate analysis of healthcare-associated, and hospital-acquired. MATERIAL AND METHODS: Prospective cohort study performed at a university tertiary care hospital over 1 year. Inclusion criteria were meeting the Centers for Disease Control definition of intra-abdominal, urinary, respiratory and bloodstream infections. RESULTS: A total of 1035 patients were included in the study. More than 25% of intra-abdominal infections were polymicrobial; multi-drug resistant gram-negatives were 38% in community-acquired, 50% in healthcare-associated and 57% in hospital-acquired. E. coli was the most prevalent among urinary infections: 69% in community-acquired, 56% in healthcare-associated and 26% in hospital-acquired; ESBL producers' pathogens were 10% in healthcare-associated and 3% in community-acquired and hospital-acquired. In respiratory infections Streptococcus pneumoniae was the most prevalent in community-acquired (54%) and MRSA in healthcare-associated (24%) and hospital-acquired (24%). A significant association was found between MRSA respiratory infection and hospitalization in the previous year (adjusted OR = 6.3), previous instrumentation (adjusted OR = 4.3) and previous antibiotic therapy (adjusted OR = 5.7); no cases were documented among patients without risk factors. Hospital mortality rate was 10% in community-acquired, 14% in healthcare-associated and 19% in hospital-acquired infection. DISCUSSION AND CONCLUSION: This study shows that healthcare-associated has a different microbiologic profile than those from community or hospital acquired for the four main focus of infection. Knowledge of this fact is important because the existing guidelines for community-acquired are | por |
| dc.description.sponsorship | Teresa Cardoso received a Scholarship for Academic Research included in Phd Thesis granted by Departamento de Formação, Ensino e Investigação do Centro Hospitalar do Porto. Funding by Associação de Apoio à Unidade de Cuidados Intensivos Polivalente, Hospital de Santo António, Porto, Portugal (ASSUCIP) | por |
| dc.identifier.citation | Cardoso T, et al. Healthcare-associated infections, Acta Med Port 2013 Jul-Aug;26(4):377-384 | por |
| dc.identifier.issn | 1646-0758 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/1635 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Centro Editor Livreiro da Ordem dos Médicos | por |
| dc.relation.publisherversion | http://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/208/3711 | por |
| dc.subject | Anti-Bacterial Agents | por |
| dc.subject | Community-Acquired Infections | por |
| dc.subject | Cross Infection | por |
| dc.subject | Delivery of Health Care | por |
| dc.subject | Urinary Tract Infections | por |
| dc.subject | Catheter-Related Infections | por |
| dc.subject | Blood-Borne Pathogens | por |
| dc.title | Differences in microbiological profile between community-acquired, healthcare-associated and hospital-acquired infections | por |
| dc.title.alternative | Diferenças no Perfil Microbiológico entre as Infecções da Comunidade, Associadas a Cuidados de Saúde e Nosocomiais | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Portugal | por |
| oaire.citation.endPage | 384 | por |
| oaire.citation.startPage | 377 | por |
| oaire.citation.title | Acta Médica Portuguesa | por |
| oaire.citation.volume | 26(4) | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |