Browsing by Author "LOPES, V."
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- Acral necrosis by Stenotrophomonas maltophiliaPublication . PEREIRA, O.; VELHO, G.C.; LOPES, V.; MOTA, F.; SANTOS, C.; MASSA, A.Keywords:necrosis;skin and soft tissue infection;Stenotrophomonas maltophilia Abstract Background Stenotrophomonas maltophilia (SM) has been considered a nosocomial pathogen. Nevertheless, community acquired infection may occur more frequently than usually recognized. Case We describe distal necrosis of the fingers by SM in a farmer, contracted in the community and successfully treated with a combination of cotrimoxazole and ciprofloxacin. The patient was diagnosed with chronic lymphocytic leukaemia 6 months later. Conclusions This unusual presentation shows that infection with SM should be included in the differential diagnosis of the skin and soft tissue infection, even in apparently healthy patients.
- Hypersomnia in Whipple disease: case report.Publication . MAIA, L.; MARTA, M.; LOPES, V.; ROCHA, N.; LOPES, C.; MARTINS‐DA‐SILVA, A.; MONTEIRO, L.Arq Neuropsiquiatr. 2006 Sep;64(3B):865-8. Hypersomnia in Whipple disease: case report. Maia LF, Marta M, Lopes V, Rocha N, Lopes C, Martins-da-Silva A, Monteiro L. SourceDepartment of Neurological Disordes and Senses, Hospital Geral de Santo António, Largo Prof. Abel Salazar, 4099-001 Porto, Portugal. Abstract Whipple disease (WD) is a rare systemic infection caused by Tropheryma whippelii. Neurological involvement has been recognised in 40% of patients, either as initial manifestations or during the course of the disease. We report on a 45 years-old man with WD with initial, persistent and irresistible episodes of daytime somnolence. The patient was HLA-DQB1*0602 positive (genetic marker for narcolepsy). WD diagnosis was suspected on clinical and MRI basis and confirmed by histological and immunohistochemical study of duodenal biopsy. Forty months later all clinical features improved, narcoleptic-like episodes disappeared and cerebral MRI and CSF normalised. Longitudinal neurophysiological studies revealed persistent sleep pattern abnormalities with sleep fragmentation, paucity of slow wave and of REM sleep. The disruption of the hypocretin circuitry in the hypothalamic - diencephalic region triggered by the infection was the probable cause of the hypersomnia and narcopleptic symptoms. WD should be added to the list of causes of secondary hypersomnia.
- Three years incidence of dermatophytes in a hospital in Porto (Portugal)Publication . LOPES, V.; VELHO, G.; AMORIM, M.L.; CARDOSO, M.L.; MASSA, A.; AMORIM, J.M.Rev Iberoam Micol. 2002 Dec;19(4):201-3. [Three years incidence of dermatophytes in a hospital in Porto (Portugal)]. [Article in Spanish] Lopes V, Velho G, Amorim ML, Cardoso ML, Massa A, Amorim JM. SourceServiço de Microbiologia, Hospital Geral Santo António, Largo Prof. Abel Salazar, 4099-001 Porto, Portugal. Abstract We evaluated the incidence of dermatophytes isolated at our hospital in the years of 1997 to 2000 and correlated it with anatomical site and age. Trichophyton rubrum was the predominant species in all anatomical sites, excluding scalp, followed by Microsporum canis, the leading agent of tinea capitis. All dermatophytosis, except tinea capitis by M. canis and Trichophyton schoenleinnii appeared mainly in adult patients. Our results revealed no substantial differences to other portuguese studies regarding the major agents. We found a relatively high incidence of T. schoenleinnii as second tinea capitis agent.