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EDCI - Artigos publicados em revistas indexadas na Medline

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  • Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease
    Publication . Feldman, H.; Maia, L.; Mackenzie, I.; Forster, B.; Martzke, J.; Woolfenden, A.
    Abstract BACKGROUND AND PURPOSE: Superficial siderosis of the central nervous system results from chronic bleeding in the superficial layers of the cortex and spinal cord. In cerebral amyloid angiopathy (CAA), there is amyloid deposition in meningeal and meningo-cortical arteries and capillaries, predisposing them to rupture. CAA is frequently associated with Alzheimer disease (AD). METHODS: We report a series of 3 AD patients with MRI evidence of superficial siderosis. Two had neuropathological examination confirming superficial siderosis, AD, and CAA. CONCLUSIONS: Superficial siderosis should be recognized within the spectrum of AD with CAA and considered as a possible antemortem diagnostic feature.
    2008Journal article Open access Show more
  • [Development of the short version of the informal caregiver burden assessment questionnaire]
    Publication . Martins, T.; Peixoto, M.; Araújo, F.; Rodrigues, M.; Pires, F.
    OBJETIVE to create a reduced version of the QASCI, which is structurally equivalent to the long one and meets the criteria of reliability and validity. METHOD Through secondary data from previous studies, the participants were divided into two samples, one for the development of reduced version and the second for study of the factorial validity. Participants responded to QASCI, the SF 36, the ADHS and demographic questions. RESULTS A reduced version of 14 items showed adequate psychometric properties of validity and internal consistency, adapted to a heptadimensional structure that assesses positive and negative aspects of care. CONCLUSION Confirmatory factor analysis revealed a good fit with the advocated theoretical model.
    2015-04Journal article Open access Show more