Browsing by Author "Lobo, I."
Now showing 1 - 10 of 15
Results Per Page
Sort Options
- Alterações cutâneas fisiológicas e transitórias do recém-nascidoPublication . Lobo, I.; Machado, S.; Selores, M.A pele desempenha um papel fundamental na protecção do recém-nascido na sua transição da vida intrauterina para a vida pós-natal. A maioria das alterações cutâneas que ocorrem neste período é fisiológica e transitória, não necessitando de procedimentos diagnósticos ou terapêutica. No entanto constituem uma fonte de preocupação dos pais, pelo que é necessário o reconhecimento destas lesões para uma abordagem adequada do recém-nascido e família. Nesta revisão os autores fazem uma discussão breve das alterações cutâneas fisiológicas e transitórias deste grupo etário. ABSTRACT Neonatal skin provides physical protection, playing a vital role in the newborn’s transition from an aqueous to an air-dominant environment. The majority of the newborn cutaneous lesions are usually physiological, transient and self limited and thus require no therapy or diagnostic procedures. As parents often seek medical attention for these problems, clinicians must be aware of both normal and abnormal cutaneous lesions of the neonate to properly address these issues. In this article the authors briefly discuss the transient benign lesions of the newborn.
- Annular elastolytic giant cell granuloma: a "visible" diagnosisPublication . Raposo, I.; Mota, F.; Lobo, I.; Brandão, J.; Selores, M.Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of undetermined cause, characterized by annular plaques with raised erythematous borders in sun-exposed skin. The typical histologic features are dermal infiltration by multinucleated giant cells, elastin degeneration, and elastophagocytosis. The authors describe a clinical case of AEGCG, which exhibited an excellent response to hydroxycloroquine.
- Calcinosis cutis: A rare feature of adult dermatomyositisPublication . Lobo, I.; Machado, S.; Teixeira, M.; Selores, M.Abstract Dermatomyositis is an idiopathic inflammatory myopathy with characteristic cutaneous manifestations. We describe a case of a 55- year-old woman with dermatomyositis who presented with dystrophic calcinosis resistant to medical treatment.
- Caso dermatológico: alergia às caneleirasPublication . Oliveira, A.; Fernandes, I.; Lobo, I.; Selores, M.Many adverse events can occur when the skin comes in contact with external agents. Eczema is one of them. The eczema can be either allergic or irritant in nature. Irritant contact dermatitis (ICD) accounts for approximately 80% of all contact dermatitis and allergic contact dermatitis (ACD) accounts for the remaining 20%. ACD is a delayed-type hypersensitivity reaction that is elicited when the skin comes in contact with a chemical to which an individual has previously been sensitized. The classic picture of contact dermatitis is a well-demarcated erythematous vesicular (in the acute form) and/or scaly patch or plaque (in the chronic form) lesion, with well-defined margins corresponding to the area of contact. It requires an appropriate level of suspicion for the possibility of an allergen to elicit a contact dermatitis. Treatment is based on avoidance of the allergen associated with corticosteroids and antihistamines. The authors present a case of allergic contact dermatitis to football shin guards in a 12 year-old boy who regularly practiced soccer.
- Caso Dermatológico: Ulerythema ophryogenesPublication . Lobo, I.; Machado, S.; Selores, M.
- [Drug rash with eosinophilia and systemic symptoms (DRESS syndrome)]Publication . Lobo, I.; Ferreira, M.; Velho, G.; Sanches, M.; Selores, M.Adverse cutaneous reactions to drugs are frequent, affecting from 2% to 3% of all hospitalized patients. But only about 2% of these cutaneous reactions are severe and seldom are fatal. The term drug hypersensitivity syndrome refers to a specific severe drug reaction, including skin rash, fever, lymph node enlargement, and single or multiple organ involvement. The cutaneous rash is usually morbilliform. The drugs associated with the syndrome are: anticonvulsants, ACE inhibitors, Beta-blockers, allopurinol and sulphonamides. The differencial diagnosis includes maculopapular rash, exfoliative dermatitis, acute generalized exanthematous pustulosis and Sézary syndrome. The interval between the starting of drug therapy and the onset of cutaneous reactions may be at least one month, and therefore the implication of the drug in the aetiology may be subdiagnosed. As reacções cutâneas a fármacos são frequentes, afectando 2 a 3% dos pacientes hospitalizados, mas só aproximadamente 2% destas são severas. O termo síndrome de hipersensibilidade a fármacos refere-se a uma reacção a fármacos caracterizada por erupção cutânea, febre, linfadenopatia e envolvimento de um ou mais órgãos sistémicos. As lesões cutâneas são normalmente morbiliformes. Os fármacos mais implicados neste tipo de reacções são os anticonvulsivantes, -bloqueadores, inibidores da enzima de conversão da angiotensina, alopurinol e as sulfamidas. O diagnóstico diferencial deverá ser feito com o exantema maculopapular, dermatite esfoliativa, pustulose exantemática aguda generalizada e com a síndrome de Sézary. As manifestações clínicas podem surgir até pelo menos um mês depois do início do fármaco, o que faz com que a implicação etiológica do mesmo possa ser subestimada. A morbilidade é alta e a mortalidade pode atingir os 10%, tornando importante o conhecimento desta patologia.
- Exuberant cutaneous ulcers on the buttocks caused by multi-resistantPublication . Pinto-Almeida, T.; Rosmaninho, A.; Lobo, I.; Alves, R.; Selores, M.Cutaneous infection develops because of environmental and local factors, host immunity, and organism adherence and virulence. The authors report a case of exuberant cutaneous ulcers on the buttocks of a diabetic patient. Microbiologic examination allowed the identification of Klebsiella pneumoniae and complete resolution was achieved with the appropriate antibiotic
- Langerhans cell histiocytosis: Two clinical presentations in the same patientPublication . Oliveira, A.; Pinto-Almeida, T.; Lobo, I.; Machado, S.; Selores, M.Langerhans cell histiocytosis (LCH) is a heterogeneous group of diseases characterized by a pathological proliferation of cells phenotypically similar to Langerhans cells. The disease course is variable, alternating between resolving and potentially fatal forms. The diagnosis is based on clinical appearance and confirmed by CD1a positivity and / or immunohistochemistry. We report the case of a male child of 3 months with two different presentations of Langerhans cell-histiocytosis (LCH) at different times. The first presentation was classified as a self-healing LCH (formerly known as Hashimoto-Pritzker). The last presentation, although clinically suggestive of Letterer-Siwe (former designation), was not associated with systemic disease. This emphasizes that LCH cannot be compartmentalized into four groups, but considered a single disease with a wide spectrum of clinical presentations. This case underscores the importance of frequent and long-term follow-up of these patients.
- Melanoma? Look closerPublication . Mota, F.; Lobo, I.; Mahia, Y.; Costa, V.; Selores, M.Pigmented skin lesions are sometimes misdiagnosed due to clinical similarities between melanocytic and non-melanocytic lesions. We report the case of a patient with a pigmented lesion that clinically resembles melanoma. With dermoscopy, observed features, namely leaf-like areas, allowed us to make the diagnosis of pigmented basal cell carcinoma. This case represents a clinical setting in which clinical examination alone could lead to a misdiagnosis, but with the use of dermoscopy an accurate diagnosis was possible.
- Perioral pigmentation: What is your diagnosis?Publication . Santos, P.; Neto, C.; Machado, S.; Lobo, I.; Soares, J.; Selores, M.Pigmented spots in the skin and mucosa (lentigines) can be found in various diseases called familial lentiginosis syndromes; Peutz-Jeghers syndrome (PJS) is one of them. It is characterized by the association of mucocutaneous melanin pigmentation and hamartomatous gastrointestinal polyps. Patients with PJS are at increased risk of intussusception and cancer development (gastrointestinal and non-gastrointestinal tumors). We present a 5-year-old girl with pigmented macules of perioral and perinasal skin, lips, and buccal mucosa and review lentiginoses and the surveillance of PJS.