SG - Sistema Gastrointestinal (Doenças hepáticas e gastrointestinais)
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- 17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological ResponsePublication . Santos, M.; Gomes, M.; Moreno, F.; Rocha, A.; Lopes, C.Neoadjuvant chemoradiation (CRT) followed by curative surgery still remains the standard of care for locally advanced rectal cancer (LARC). The main purpose of this multimodal treatment is to achieve a complete pathological tumor response (ypCR), with better survival. The surgery delay after CRT completion seems to increase tumor response and ypCR rate. Usually, time intervals range from 8 to 12 weeks, but the maximum tumor regression may not be seen in rectal adenocarcinomas until several months after CRT. About this issue, we report a case of a 52-year-old man with LARC treated with neoadjuvant CRT who developed, one month after RT completion, an acute myocardial infarction. The need to increase the interval between CRT and surgery for 17 weeks allowed a curative surgery without morbidity and an unexpected complete tumor response in the resected specimen (given the parameters presented in pelvic magnetic resonance imaging (MRI) performed 11 weeks after radiotherapy completion).
- Anorectal melanoma: an uncommon and aggressive diseasePublication . Magalhães, M.; Salgado, M.; Pedroto, I.
- Caso Endoscópico: colonização do esófago por Cândida AlbicansPublication . Pereira, F.
- Caso endoscópico: Doença de CrohnPublication . Pereira, F.ABSTRACT A case of a fourteen years old boy with complaints of dispepsia in the last 2 months associated with anorexia end weight loss is presented. He had frequent bowel movements (4-5 times a day), some during the night, for the last one and a half year. He presented hypocromic microcytic anemia with low serum iron and ferritin, and elevated values of ESR and PCR. The upper digestive endoscopy showed ulcerative esophagitis with inflammatory infiltrate of the mucosa, with the participation of lymphocytes, plasmocytes and neutrophils but without eosinophils. Colonoscopy and colon biopsies confirmed the diagnosis of Crohn colitis. Diagnosis: Crohn disease with esophageal lesions.
- Caso endoscópico: Esofagite eosinofílicaPublication . Pereira, F.A six year-old boy presented with chronic nocturnal cough. History of bronchial asthma controlled with medical treatment, alergy to house dust and acarus. Upper endoscopy and biopsy confirmed criteria for eosinophilic esophagitis. There was a good response to swallowed fluticasone.
- Caso endoscópico: esofagite gravePublication . Pereira, F.ABSTRACT We present the case of a eight-year old boy with microcytic hypochromic anemia, who refused to ingest meat products for the last years. He had a good response to therapy with oral iron supplements, but with further recurrence of symptoms after stopping treatment. Investigation by Haematology was inconclusive. The upper endoscopy showed severe peptic esophagitis with stenosis. The patient was treated with proton pump inhibitors, dilation of the stenosis and surgery (Nissen fundoplication), with good outcome.
- Caso Endoscópico: Manifestação esofágica da Disqueratose CongénitaPublication . Pereira, F.
- Caso Endoscópico: Obstrução esofágica por corpo estranhoPublication . Pereira, F.
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